辛博学应用程序

互动应用，以方便构建，模拟和分析动态系统

SimBiology provides a set of integrated apps that are designed to facilitate building, simulating, and analyzing models of dynamic systems such as quantitative systems pharmacology (QSP), pharmacokinetic/pharmacodynamic (PK/PD) and systems biology models.

TheSimBiology Model Builderapp lets you build dynamic models interactively using various modeling elements. For instance, you can model a variety of biological systems such as signaling pathways, metabolic networks, PBPK, QSP, and PK/PD models. It also lets you model biological variability and different dosing regimens to investigate various experimental conditions and dosing strategies.
TheSimBiology Model Analyzerapp lets you perform analyses on models of dynamic systems. You can simulate the dynamic behavior of a model using various solvers and estimate model parameters. To investigate system dynamics and guide experimentation, you can perform sensitivity analysis and parameter sweeps.

Apps

SimBiology Model Builder	Build QSP, PK/PD, and mechanistic systems biology models interactively
SimBiology Model Analyzer	Analyze QSP, PK/PD, and mechanistic systems biology models

Functions

`simbio.diagram.getBlock`	Get SimBiology diagram block properties
`simbio.diagram.setBlock`	设置Simbiology图块属性
`simbio.diagram.getLine`	Get SimBiology diagram line properties
`simbio.diagram.setLine`	设置Simbiology图线属性
`simbio.diagram.splitBlock`	Split SimBiology species block in diagram
`simbio.diagram.joinBlock`	Combine all copies of SimBiology species blocks in diagram

Topics

Build Models

Create Model of Receptor-Ligand Kinetics

此示例显示如何使用该示例如何创建和模拟受体 - 配体动力学的简单模型SimBiology Model Builder和SimBiology Model Analyzerapps.

Incorporate SGLT2 Inhibition into Physiologically Based Glucose-Insulin Model Using SimBiology Model Builder

Incorporate sodium-glucose co-transporter 2 (SGLT2) receptor inhibition by a hypothetical compound into an existing glucose-insulin model.

Copy SimBiology Blocks

在图表中构建模型时复制和粘贴辛生物块。

Keyboard Shortcuts for SimBiology Model Builder

TheSimBiology Model Builderapp provides keyboard shortcuts for various modeling actions.

SimBiology Model Component Libraries

The SimBiology^®libraries are collections of built-in components that you can use to build and analyze models.

消息指示器图标在素质模型建设者中

TheSimBiology Model Builderapp uses contextual icons to provide more information about model components in the browser tables and blocks in theDiagramtab.

Undo and Redo Model Changes in SimBiology

You can undo and redo actions related to model building and configuring block properties.